Biology· pathway-reasoning
BioMaze
Peking University · 2025
5.1K real-research pathway problems testing LLM reasoning over biological pathways and perturbations.
Biology
Examples
Browse full dataset ↗question
In the context of guanylyl cyclase activating protein 1 (GCAP-1) function, does the inactivation of magnesium ion (Mg(2+)) binding in EF-hand 3 lead to a reduction in GCAP-1 affinity for retinal guanylyl cyclase (RetGC)?
answer
Yes
abs_id
PMID:17545152
Inquiry Type
Perturbed
Extra Condition
Natural
Investigation Target
Interaction
biocategory
Organismal Systems
biosubcategory
Sensory system
question
In cultured rat vascular smooth muscle cells (VSMC) stimulated with angiotensin II (Ang II), does the addition of propranolol lead to an increase in the production of phosphatidic acid (PA)?
answer
Yes
abs_id
PMID:10666319
Inquiry Type
Perturbed
Extra Condition
Intervened
Investigation Target
Function
biocategory
Environmental Information Processing
biosubcategory
Signal transduction
Real rows from the Hugging Face datasets server · long values truncated